Protein Domain : Bifunctional purine biosynthesis protein PurH-like IPR002695

Type  Family
Description  This is a family of bifunctional enzymes catalysing the last two steps in de novopurine biosynthesis. The bifunctional enzyme is found in both prokaryotes and eukaryotes. The second last step is catalysed by 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), this enzyme catalyses the formylation of AICAR with 10-formyl-tetrahydrofolate to yield FAICAR and tetrahydrofolate [ ]. The last step is catalysed by IMP (Inosine monophosphate) cyclohydrolase (IMPCHase), cyclizing FAICAR (5-formylaminoimidazole-4-carboxamide ribonucleotide) to IMP [ ].
Short Name  PurH-like

0 Child Features

1 Gene Families

157 Genes

3 Ontology Annotations

0 Parent Features

14 Publications

USDA
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