Protein Domain : AICAR transformylase, duplicated domain superfamily IPR024051

Type  Homologous_superfamily
Description  This domain is found in the enzyme 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT). AICARFT can be part of a bifunctional enzyme catalysing the last two steps in de novopurine biosynthesis and having also an IMP (Inosine monophosphate) cyclohydrolase (IMPCHase) functional domain. The bifunctional enzyme forms an intertwined dimer where each monomer is composed of two separate functional domains. This superfamily represents a duplicated domain in AICARFT consisting of a three layer α-β-alpha sandwich [ ].
Short Name  AICAR_Tfase_dup_dom_sf

0 Child Features

1 Gene Families

115 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom