Protein Domain : RNase L inhibitor RLI-like, possible metal-binding domain IPR007209

Type  Domain
Description  This is part of a possible metal-binding domain in endoribonuclease RNase L inhibitor. It is found at the N-terminal end of RNase L inhibitor proteins, adjacent to the 4Fe-4S binding domain, . Also often found adjacent to in uncharacterised proteins. The RNase L system plays a major role in the anti-viral and anti-proliferative activities of interferons [ ]. It is a component of the multifactor complex (MFC) involved in translation initiation and it is required for the processing and nuclear export of the 60S and 40S ribosomal subunits, playing a role in ribosome biogenesis [, . Inhibitory activity requires concentration-dependent association of RLI with RNase L [ ].
Short Name  RNaseL-inhib-like_metal-bd_dom

0 Child Features

1 Gene Families

164 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom