v5.1.0.3
Glycine data from LIS
Type | Family |
Description | COG6 is a component of the peripheral membrane COG (conserved oligomeric Golgi) complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, regulates tethering of retrograde intra-Golgi vesicles and is required for normal Golgi morphology and localisation [ , , ]. COG subunits belong to the CATCHR (complexes associated with tethering containing helical rods) family which includes subunits of the GARP/EARP, exocyst, and Dsl1 complexes, all evolutionary related and have a conserved structural fold consisting of α-helical bundles in tandem at the C-terminal and a coiled-coil region at the N-terminal [, ]. |
Short Name | COG6 |