v5.1.0.3
Glycine data from LIS
Type | Active_site |
Description | Glycoside hydrolase family 1 comprises enzymes with a number of known activities; beta-glucosidase ( ); beta-galactosidase ( ); 6-phospho-beta-galactosidase ( ); 6-phospho-beta-glucosidase ( ); lactase-phlorizin hydrolase ( )/( ); beta-mannosidase ( ); myrosinase ( ). This entry represents a conserved region found in these enzymes. It is centred on a conserved glutamic acid residue which has been shown in the beta-glucosidase from Agrobacterium, to be directly involved in glycosidic bond cleavage by acting as a nucleophile. Signature in this entry also picks up the last two domains of LPH (lactase-phlorizin hydrolase); the first two domains, which are removed from the LPH precursor by proteolytic processing, have lost the active site glutamate and may therefore be inactive [ ]. |
Short Name | Glyco_hydro_1_AS |