Ontology Term : Pfam:PF08235 LNS2 (Lipin/Ned1/Smp2) EMBL-EBI

Description  This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain (Pfam: PF04571) [1]. SMP2 (also known as PAH1) is involved in plasmid maintenance and respiration [2], and has been identified as a Mg2+-dependent phosphatidate phosphatase (EC:3.1.3.4) that contains a haloacid dehalogenase (HAD)-like domain [4]. Lipin proteins are involved in adipose tissue development and insulin resistance [3].
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1 Ontology

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