Protein Domain : Phospholipase C/P1 nuclease domain superfamily IPR008947

Type  Homologous_superfamily
Description  The enzymes belonging to this superfamily are involved in phosphate ester hydrolysis and contain a triad of closely spaced zinc ions at their active centres. Both families of enzymes hydrolyse phosphodiesters. Substrates for phospholipase C are phosphatidylinositol and phosphatidylcholine, while P1 nuclease is an endonuclease hydrolysing single stranded ribo- and deoxyribonucleotides. P1 nuclease also has activity as a phosphomonoesterase against 3'-terminal phosphates of nucleotides. The Zn ions in both enzymes form almost identical trinuclear sites [ ].
Short Name  PLipase_C/P1_nuclease_dom_sf

0 Child Features

3 Gene Families

507 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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