v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | RNA polymerases ( ) catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (notincluding mitochondrial and chloroplast polymerases). This domain represents the hybrid-binding domain and the wall domain []. Thehybrid-binding domain binds the nascent RNA strand/template DNA strand in the Pol II transcription elongation complex. This domain contains the important structuralmotifs, switch 3 and the flap loop and binds an active site metal ion [ ]. This domain is also involved in binding to Rpb1 and Rpb3[ ]. Many of the bacterial members contain large insertionswithin this domain, which are known as dispensable region 2 (DRII). |
Short Name | DNA-dir_RNAP_su2_dom |