v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This entry represents the adenylation domain of the mRNA capping enzyme [ ]. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an RNA 5'-triphosphatase []. Binding of the enzyme to nucleotides is specific to the GMP moiety of GTP. The viral mRNA capping enzyme is a monomer that transfers a GMP cap onto the end of mRNA that terminates with a 5'-diphosphate tail.It contains a catalytic core composed of an adenylation domain and a C-terminal OB-fold domain containing conserved sequence motifs. The adenylation domain binds ATP and contains many active site residues [, ]. |
Short Name | mRNA_cap_enzyme_adenylation |