v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This domain is found in lipins and lipin homologues from Saccharomyces cerevisiae (Smp2) and from Schizosaccharomyces pombe (Ned1) [ ]. Smp2 (also known as PAH1) is involved in plasmid maintenance and respiration [] and has been identified as a Mg2+-dependent phosphatidate phosphatase () that contains a haloacid dehalogenase (HAD)-like domain [ ]. Lipin proteins are phosphatidate phosphatases which catalyse the dephosphorylation of phosphatidic acid to diacylglycerol, the penultimate step in triacylglycerol synthesis []. They are involved in adipose tissue development and insulin resistance []. |
Short Name | LNS2 |