Protein Domain : Lipin/Ned1/Smp2 (LNS2) IPR013209

Type  Domain
Description  This domain is found in lipins and lipin homologues from Saccharomyces cerevisiae (Smp2) and from Schizosaccharomyces pombe (Ned1) [ ]. Smp2 (also known as PAH1) is involved in plasmid maintenance and respiration [] and has been identified as a Mg2+-dependent phosphatidate phosphatase () that contains a haloacid dehalogenase (HAD)-like domain [ ]. Lipin proteins are phosphatidate phosphatases which catalyse the dephosphorylation of phosphatidic acid to diacylglycerol, the penultimate step in triacylglycerol synthesis []. They are involved in adipose tissue development and insulin resistance [].
Short Name  LNS2

0 Child Features

2 Gene Families

420 Genes

0 Ontology Annotations

1 Parent Features

14 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom