Protein Domain : PA2G4 family IPR004545

Type  Family
Description  Proteins of this family have been identified in a number of species as a nuclear protein with a cell cycle dependence. Various names have been given to members of this family which include cell cycle protein p38-2G4, also known as proliferation-associated protein PA2G4 [ , ], curved DNA-binding protein [], proliferation-associated protein A, and ErbB3-binding protein 1 (Ebp1) []. They constitute the proliferation-associated PA2G4 family, which is structurally homologous to the type II methionine aminopeptidases, but without methionine aminopeptidase activity [, ]. ErbB3 binding protein-1 (Ebp1) is a potential regulator of ErbB3 signaling, and is implicated in cell growth, apoptosis and differentiation in many cell types [, ].These proteins are classified as non-peptidase homologues in the MEROPS peptidase family M24 (clan MG).
Short Name  PA2G4

0 Child Features

1 Gene Families

198 Genes

0 Ontology Annotations

1 Parent Features

14 Publications

USDA
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