v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This entry represents a domain found in hydrolase enzymes that belong to the isochorismatase family, including Ureidoacrylate amidohydrolase RutB from Escherichia coli and Nicotinamidase from Saccharomyces cerevisiae. Isochorismatase (also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase) catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate [ ]. This domain shows a typical helix-sheet-helix sandwich structural architecture, with a central β-sheet made of six parallel strands, three α-helices on one side and two α-helices on the other []. |
Short Name | Isochorismatase-like |