LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Conserved_site |
| Description | Ubiquitin-activating enzyme (E1 enzyme) [ , ] activates ubiquitin by firstadenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding anubiquitin-E1 thiolester and free AMP. Later the ubiquitin moiety is transferred to a cysteine residue on one of the many forms of ubiquitin-conjugating enzymes (E2). E1 is a large monomeric protein of about 110 to 115 Kd (about 1000 residues). In yeast there are two forms (UBA1 and UBA2) [], while in plants and mammalsmultiple forms exist including a form which is Y-linked in mouse and some other mammals and which may be involved in spermatogenesis.It has been shown that the last of the five cysteines that are conserved in the sequence of E1 from various species is the one that binds ubiquitin [ ]. This entry represents a conserved region containing the second of the five conserved cysteines. |
| Short Name | UBQ-activ_enz_E1_CS |
