Protein Domain : Sodium/calcium exchanger membrane region IPR004837

Type  Domain
Description  The sodium/calcium exchangers are a family of integral membrane proteins. This domain covers the integral membrane regions of these proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells [ ]. Ca2+ is moved into or out of the cytosol depending on Na+ concentration []. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3 [].
Short Name  NaCa_Exmemb
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0 Child Features

7 Gene Families

Trail: ProteinDomain

1000 Genes

Trail: ProteinDomain

2 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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