Protein Domain : 2-oxoacid dehydrogenase acyltransferase, catalytic domain IPR001078

Type  Domain
Description  This domain is found in the lipoamide acyltransferase component of the branched-chain alpha-keto acid dehydrogenase complex , which catalyses the overall conversion of alpha-keto acids to acyl-CoA and carbon dioxide [ ]. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamideacyltransferase (E2) and lipoamide dehydrogenase (E3). The domain is also found in the dihydrolipoamide succinyltransferase component of the 2-oxoglutarate dehydrogenase complex . These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain.
Short Name  2-oxoacid_DH_actylTfrase

0 Child Features

3 Gene Families

669 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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