Protein Domain : Acylneuraminate cytidylyltransferase IPR003329

Type  Family
Description  Synonym(s): CMP-N-acetylneuraminic acid synthetaseAcylneuraminate cytidylyltransferase ( ) (CMP-NeuAc synthetase) catalyzes the reaction of CTP and NeuAc to form CMP-NeuAc, which is the nucleotide sugar donor used by sialyltransferases [ ]. The outer membrane lipooligosaccharides of some microorganisms contain terminal sialic acid attached to N-acetyllactosamine and so this modification may be important in pathogenesis.This family also includes 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase found in the bacterial genus Shewanella, which is important in the development of the outer cell membrane and converts 3-deoxy-d-manno-octulosonic acid to 8-amino-3,8-dideoxy-d-manno-octulosonic acid (KDO8N) for incorporation into the lipopolysaccharide [ ].
Short Name  Cytidylyl_trans

2 Child Features

1 Gene Families

111 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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