Protein Domain : Multiprotein bridging factor 1, N-terminal IPR013729

Type  Domain
Description  This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex [ ]. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC []. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif () is found to its C terminus.
Short Name  MBF1_N

0 Child Features

2 Gene Families

170 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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