Protein Domain : Ketol-acid reductoisomerase IPR013023

Type  Family
Description  Ketol-acid reductoisomerase (KARI) or acetohydroxy acid isomeroreductase catalyses the conversion of acetohydroxy acids into dihydroxy valerates. This reaction is the second in the synthetic pathway of the essential branched side chain amino acids valine and isoleucine [ ]. The enzyme forms a tetramer of similar but non-identical chains, and requires magnesium as a cofactor. Most ketol-acid reductoisomerases prefer the NADPH cofactor to NADH, but NADH-utilizing enzymes has also been identified [].
Short Name  KARI

3 Child Features

1 Gene Families

274 Genes

2 Ontology Annotations

0 Parent Features

14 Publications

USDA
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