LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Family |
| Description | In Saccharomyces cerevisiae, Nucleolar complex protein 2 (Noc2) forms a nucleolar complex with Mak21 that binds to 90S and 66S pre-ribosomes. It also forms a nuclear complex with Noc3 that binds to 66S pre-ribosomes [ ]. Both complexes mediate intranuclear transport of ribosomal precursors []. In humans, Noc2 (also known as NIR) acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. It also acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. It is involved in the regulation of p53/TP53-dependent apoptosis [ , , ].Nucleolar complex-associated protein 2 (Noc2) from Arabidopsis thaliana appears to be involved in pre-ribosome export from the nucleus to the cytoplasm [ ]. Also from A.thaliana, Protein REBELOTE influences floral meristem (FM) determinacy in an AGAMOUS and SUPERMAN-dependent manner, thus contributing to the floral developmental homeostasis []. |
| Short Name | Noc2 |
