Protein Domain : Phytochelatin synthase, C-terminal IPR015407

Type  Domain
Description  This entry represents the C-terminal region of plant phytochelatin synthases (also known as glutathione gamma-glutamylcysteinyltransferase; ), which is involved in the synthesis of phytochelatins (PC) and homophytochelatins (hPC), the heavy-metal-binding peptides of plants. This enzyme is required for detoxification of heavy metals such as cadmium and arsenate. The N-terminal region of phytochelatin synthase contains the active site, as well as four highly conserved cysteine residues that appear to play an important role in heavy-metal-induced phytochelatin catalysis. The C-terminal region is rich in cysteines, and may act as a metal sensor, whereby the Cys residues bind cadmium ions to bring them into closer proximity and transferring them to the activation site in the N-terminal catalytic domain [ ]. The C-terminal region displays homology to the functional domains of metallothionein and metallochaperone.
Short Name  Phytochelatin_synthase_C

0 Child Features

1 Gene Families

286 Genes

4 Ontology Annotations

0 Parent Features

14 Publications

USDA
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