Protein Domain : Polyadenylate-binding protein/Hyperplastic disc protein IPR002004

Type  Domain
Description  The polyadenylate-binding protein (PABP) has a conserved C-terminal domain (PABC), which is also found in the hyperplastic discs protein (HYD) family of ubiquitin ligases that contain HECT domains ( ) [ ]. PABP recognises the 3' mRNA poly(A) tail and plays an essential role in eukaryotic translation initiation and mRNA stabilisation/degradation. PABC domains of PABP are peptide-binding domains that mediate PABP homo-oligomerisation and protein-protein interactions. In mammals, the PABC domain of PABP functions to recruit several different translation factors to the mRNA poly(A) tail [].
Short Name  PABP_HYD

0 Child Features

1 Gene Families

707 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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