Protein Domain : Ion transport domain IPR005821

Type  Domain
Description  This domain is found in sodium, potassium, and calcium ion channels proteins. The proteins have 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some Na channel proteins the domain is repeated four times, whereas in others (e.g. K channels) the protein forms a tetramer in the membrane. A bacterial structure of the protein is known for the last two helices but is not included in the Pfam family due to it lacking the first four helices.
Short Name  Ion_trans_dom

0 Child Features

7 Gene Families

1000 Genes

4 Ontology Annotations

0 Parent Features

14 Publications

USDA
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