Protein Domain : PHD finger protein 20, AT hook IPR022255

Type  Domain
Description  PHD finger protein 20 (PHF20) is a Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. It consists of tandem Tudor domains at the N-terminal, an AT hook, a C2H2-type zinc finger, and a plant homeodomain (PHD) finger [ , , ]. PHF20L1 binds to monomethylated lysine 142 on DNA (cytosine-5) methyltransferase 1 (DNMT1). It has been shown to antagonize DNMT1 proteasomal degradation [].This is the AT-hook domain found in PHD finger protein 20 (PHF20) and PHD finger protein 20-like (PHF20L) [ , , ].
Short Name  PHF20_AT-hook
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