LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Homologous_superfamily |
| Description | Peroxidases are haem-containing enzymes that use hydrogen peroxide as the electron acceptor to catalyse a number of oxidative reactions.Most haem peroxidases follow the reaction scheme: Fe3++ H 2O 2-->[Fe 4+=O]R' (Compound I) + H2O [Fe4+=O]R' + substrate -->[Fe 4+=O]R (Compound II) + oxidised substrate[Fe4+=O]R + substrate -->Fe 3++ H 2O + oxidised substrate In this mechanism, the enzyme reacts with one equivalent of H 2O 2to give [Fe4+=O]R' (compound I). This is a two-electron oxidation/reduction reaction where H 2O 2is reduced to water and the enzyme is oxidised. One oxidising equivalent resides on iron, giving the oxyferryl [] intermediate, while in many peroxidases the porphyrin (R) is oxidised to the porphyrin pi-cation radical (R'). Compound I then oxidises an organic substrate to give a substrate radical [ ].Haem peroxidases include two superfamilies: one found in bacteria, fungi, plants and the second found in animals. The animal peroxidases comprise a group of homologous proteins that differ markedly from the plant/fungal/bacterial peroxidases in primary, secondary and tertiary structure, but which share with them a common function. Animal peroxidases probably arose independently of the plant/fungal/bacterial peroxidase superfamily and most likely belong to a different gene family. The crystal structures of a number of these proteins show that the active sites of animal peroxidase and plant/fungal/bacterial peroxidases are remarkably similar [ ]. |
| Short Name | Haem_peroxidase_sf |
