Protein Domain : Ornithine aminotransferase IPR010164

Type  Family
Description  Ornithine aminotransferase catalyses the conversion of L-ornithine and a 2-oxo acid to L-glutamate 5-semialdehyde and an L-amino acid. This enzyme is found in low-GC bacteria, where it is responsible for the fourth step in arginine biosynthesis, and in the mitochondrial matrix of eukaryotes, where it controls L-ornithine levels in tissues. In human hereditary ornithine aminotransferase deficiency, the elevated levels of intraocular concentrations of ornithine are responsible for gyrate atrophy, which affects the CNS and peripheral nervous system [ ].
Short Name  Orn_aminotrans

1 Child Features

0 Gene Families

335 Genes

1 Ontology Annotations

1 Parent Features

13 Publications

USDA
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