Protein Domain : Transmembrane protein 176A/B IPR009281

Type  Family
Description  Transmembrane (TMEM)-176A and 176B proteins are closely related to MS4A (membrane-spanning 4-domains subfamily A) proteins [ ]. Their levels are significantly elevated in certain cancers [, ]. TMEM176B (LR8, Torid, Clast1) is broadly expressed, but was up regulated in antigen presenting cells in a rat model of allograft tolerance []. Their role in the immune system is unclear.
Short Name  TMEM176A/TMEM176B
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