Protein Domain : RNA polymerase Rpb7-like, N-terminal domain superfamily IPR036898

Type  Homologous_superfamily
Description  The eukaryotic RNA polymerase subunits RPB4 and RPB7 form a heterodimer that reversibly associates with the RNA polymerase II core, being involved in initiation complex formation [ ]. Archaeal cells contain a single RNAP made up of about 12 subunits, displaying considerable homology to the eukaryotic RNAPII subunits. The RPB4 and RPB7 homologues are called subunits F and E, respectively, and have been shown to form a stable heterodimer. While the RPB7 homologue is reasonably well conserved, the similarity between the eukaryotic RPB4 and the archaeal F subunit is barely detectable [].This entry represents the N-terminal, heterodimerisation domain superfamily of RPB7 and homologues. This domain has a beta-α-β(2) fold arranged in two layers (alpha/beta) with antiparallel β-sheet.
Short Name  RNA_pol_Rpb7-like_N_sf

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