Protein Domain : dTDP-4-dehydrorhamnose reductase family IPR005913

Type  Family
Description  dTDP-4-dehydrorhamnose reductase ( ) catalyses the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose, which is the final step in the conversion of dTDP-D-glucose to dTDP-L-rhamnose [ ]. dTDP-rhamnose is essential for growth of mycobacteria []. dTDP-L-rhamnose is the precursor of L-Rhamnose (L-Rha), a component of the lipopolysaccharide (LPS) core and several O antigen polysaccharides of Pseudomonas [].Methionine adenosyltransferase 2 subunit beta (MAT2B) also belongs to this family. It is the regulatory subunit of MAT2A, an enzyme that catalyses the formation of S-adenosylmethionine (AdoMet) from methionine and ATP [ ]. Also in this family is the probable dTDP-4,6-dihydroxy-2-methyloxan-3-one 4-ketoreductase (oleU) from Streptomyces antibioticus, which is required for the biosynthesis of the aglycone antibiotic oleandomycin [ ].
Short Name  dTDP_dehydrorham_reduct

0 Child Features

3 Gene Families

626 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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