Protein Domain : Major surface glycoprotein G IPR000925

Type  Family
Description  Respiratory synctial virus (RSV) has two major virion envelope proteins, the fusion F and major attachment G glycoproteins, which are the two viral neutralisation antigens []. This entry represents the major surface glycoprotein G from RSV. G glycoprotein interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection [, ]. There are two versions of the G protein: the full length G protein (mG), which is anchored by a transmembrane domain near the N terminus; the secreted version (sG), which lacks the transmembrane domain due to an alternative initiation of translation []. The secreted version-sG helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy [].
Short Name  G_prot

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

0 Parent Features

0 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom