v5.1.0.3
Glycine data from LIS
Type | Family |
Description | Respiratory synctial virus (RSV) has two major virion envelope proteins, the fusion F and major attachment G glycoproteins, which are the two viral neutralisation antigens []. This entry represents the major surface glycoprotein G from RSV. G glycoprotein interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection [, ]. There are two versions of the G protein: the full length G protein (mG), which is anchored by a transmembrane domain near the N terminus; the secreted version (sG), which lacks the transmembrane domain due to an alternative initiation of translation []. The secreted version-sG helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy []. |
Short Name | G_prot |