GO Term : GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity Gene Ontology
Description  Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
Namespace  molecular_function
Obsolete  false
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