Protein Domain : BrxC IPR022551

Type  Family
Description  Bacillithiol (BSH) functions as a general thiol reductant, analogous to glutathione, in a wide range of bacterial species. Bacilliredoxins reduce those proteins that are modified by disulfide bond formation with BSH (S-bacillithiolation) [ ].This entry represents BrxC from Bacillus subtilis (formerly known as YtxJ) and similar bacterial proteins related to BSH. BrxC is a monothiol bacilliredoxin responsible for the removal of BSH from oxidized cytosolic proteins. It can also debacillithiolate the mixed disulfide form of the bacilliredoxin BrxB [ , ]. It has a similar fold to thioredoxin.The homologue in Deinococcus radiodurans, named AbxC, plays a role in the response to oxidative stress [ ].
Short Name  BrxC
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