Protein Domain : Orotate phosphoribosyltransferase IPR023031

Type  Family
Description  Orotate phosphoribosyltransferase (OPRTase) is involved in the biosynthesis of pyrimidine nucleotides. In the pyrimidine synthesis pathway, OPRT catalyses the reversible phosphoribosyl transfer from 5'-phospho-alpha-D-ribose 1'-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5'-monophosphate (OMP) [ ]. The structures and properties of the OPRTases from different species have been described in several publications [, , , ].
Short Name  OPRT
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1 Child Features

Trail: ProteinDomain

1 Gene Families

Trail: ProteinDomain

109 Genes

Trail: ProteinDomain

2 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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