Protein Domain : 3-hydroxyisobutyrate dehydrogenase-related IPR015815

Type  Family
Description  This entry contains related reductases/dehydrogenases:3-hydroxyisobutyrate dehydrogenase (HIBADH) ( ) catalyzes the NAD-dependent, reversible oxidation of 3-hydroxbutyrate to methylmalonate [ ]. In eukaryotes, it is a homodimeric mitochondrial protein involved in valine catabolism. In Pseudomonas aeruginosa [] (gene mmsB), it is involved in the distal valine metabolic pathway.2-hydroxy-3-oxopropionate reductase ( ) catalyses the NAP(P)H dependent reduction of 2-hydroxy-3-oxopropionate (tartronate semialdehyde) to D-glycerate. 2-(hydroxymethyl)glutarate dehydrogenase ( ) catalyses the conversion of 2-formylglutarate to (S)-2-hydroxymethylglutarate [].L-threonate dehydrogenase catalyses oxidation of L-threonate to 2-oxo-tetronate [ ].Putative oxidoreductase GLYR1, also known as 3-hydroxyisobutyrate dehydrogenase-like protein or nuclear protein NP60, which regulates p38 MAP kinase activity [ ].
Short Name  HIBADH-related

3 Child Features

9 Gene Families

883 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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