Protein Domain : Sigma intracellular receptor 2 IPR016964

Type  Family
Description  Sigma-2 receptor, also known as TMEM97, is an intracellular orphan receptor highly expressed in various rapidly proliferating cancer cells and regarded as a cancer cell biomarker. It is a cytochrome-related protein that binds to various pharmacological compounds, and modulates the cytosolic Ca2+ concentration, dopaminergic transmission, and cocaine-induced addiction behavior [ , , ]. It may have a role as regulator of cellular cholesterol homeostasis [] and function as a sterol isomerase [].
Short Name  Sigma2_recept
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0 Child Features

1 Gene Families

Trail: ProteinDomain

110 Genes

Trail: ProteinDomain

0 Ontology Annotations

0 Parent Features

14 Publications

Trail: ProteinDomain
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