Protein Domain : Kynurenine formamidase/cyclase-like IPR007325

Type  Family
Description  Kynurenine formamidase catalyses the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation [ ]. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site.This family also includes cyclase-like proteins from plants. They are involved in responses to abiotic stress, and could function as polyketide cyclases [ ]. Isatin hydrolase (), characterized from the bacterium Labrenzia aggregata, is also a member of this family. It is a manganese-binding enzyme that hydrolyses the cyclic amide bond (lactam) of isatin (1H-indole-2,3-dione) to yield isatinate (2-(2-aminophenyl)-2-oxoacetate), during the degradation of the plant hormone indole-3-acetic acid (IAA) [ ].
Short Name  KFase/CYL

1 Child Features

1 Gene Families

330 Genes

2 Ontology Annotations

0 Parent Features

14 Publications

USDA
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