v5.1.0.3
Glycine data from LIS
Type | Family |
Description | Kynurenine formamidase catalyses the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation [ ]. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site.This family also includes cyclase-like proteins from plants. They are involved in responses to abiotic stress, and could function as polyketide cyclases [ ]. Isatin hydrolase (), characterized from the bacterium Labrenzia aggregata, is also a member of this family. It is a manganese-binding enzyme that hydrolyses the cyclic amide bond (lactam) of isatin (1H-indole-2,3-dione) to yield isatinate (2-(2-aminophenyl)-2-oxoacetate), during the degradation of the plant hormone indole-3-acetic acid (IAA) [ ]. |
Short Name | KFase/CYL |