Protein Domain : GTP-binding protein LepA, C-terminal IPR013842

Type  Domain
Description  The elongation factor 4 (LepA or GUF1 in Saccaromyces) is a GTP-binding membrane protein related to EF-G and EF-Tu. LepA is a noncanonical GTPase that has an unknown function. It is highly conserved and present in bacteria, mitochondria, and chloroplasts [ ]. LepA contains domains that are homologous to EF-G domain I, II, III, V. However, it also contains a C-terminal domain (CTD) that is not homologous to any region in EF-G. This entry represents the unique C-terminal region of LepA [ ]. The CTD of LepA may play a primary role in back translocation by providing additional binding interactions with a back-translocated tRNA [].
Short Name  LepA_CTD

0 Child Features

1 Gene Families

216 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

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