LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Description | This family consists of several Rab5-interacting proteins (RIP5 or Rab5ip) including ER membrane protein complex subunit 6 (EMC6) and RCAF1. The ras-related GTPase rab5 is rate-limiting for homotypic early endosome fusion. Rab5ip represents a novel rab5 interacting protein that may function on endocytic vesicles as a receptor for rab5-GDP and participate in the activation of rab5 [1]. EMC6 interacts with Rab5A and BECN1/Beclin 1 and regulates autophagosome formation [2]. EMC6 is part of the EMC complex, required for efficient folding of proteins in the ER [3] and for post-translational membrane insertion of tail-anchored (TA) proteins [4,5]. |
| Namespace | Family |
