v5.1.0.3
Glycine data from LIS
Type | Conserved_site |
Description | Glutamate 5-kinase ( ) (gamma-glutamyl kinase) (GK) is the enzyme that catalyzes the first step in the biosynthesis of proline from glutamate, the ATP-dependent phosphorylation of L-glutamate into L-glutamate 5-phosphate. In eubacteria (gene proB) and yeast [ ] (gene PRO1), GK is a monofunctionalprotein, while in plants and mammals, it is a bifunctional enzyme (P5CS) [ ] that consists of two domains: a N-terminal GK domain and a C-terminal gamma-glutamyl phosphate reductase domain ( ). This entry represents a highly conserved glycine-and alanine- rich region located in the central section of these enzymes. |
Short Name | Glutamate_5-kinase_CS |