v5.1.0.3
Glycine data from LIS
Type | Conserved_site |
Description | A number of enzymes have been shown to be functionally as well as evolutionary related []. The nifV and leuA genes encode homocitrate synthase and alpha-isopropylmalate synthase, respectively The N-terminal parts of NifV and LeuA from bacteria are highly similar to each other []. Homocitrate synthase () (gene nifV) is involved in the biosynthesis of the iron-molybdenum cofactor of nitrogenase and catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate into homocitrate. Alpha-isopropylmalate synthase ( ) catalyses the first step in the biosynthesis of leucine, the condensation ofacetyl-CoA and alpha- ketoisovalerate to form 2-isopropylmalate synthase. |
Short Name | AIPM/Hcit_synth_CS |