Protein Domain : DNA/RNA-binding protein Alba-like IPR002775

Type  Domain
Description  Members of this group include the archaeal protein Alba and eukaryotic Ribonuclease P subunits Pop7/Rpp20 and Rpp25. The Alba domain is closely related to the RNA-binding versions of the IF3-C fold such as YhbY and IF3-C. The eukaryotic lineages of the Alba family are principally involved in RNA metabolism, suggesting that the ancestral function of the IF3-C fold was related to RNA interaction [ ].Alba has been shown to bind DNA and affect DNA supercoiling in a temperature dependent manner [ ]. It is regulated by acetylation (alba = acetylation lowers binding affinity) by the Sir2 protein. Alba is proposed to play a role in establishment or maintenance of chromatin architecture and thereby in transcription repression. For further information see [].
Short Name  DNA/RNA-bd_Alba-like

0 Child Features

5 Gene Families

791 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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