Protein Domain : SS18, N-terminal IPR007726

Type  Domain
Description  This entry represents the N-terminal domain of SS18 and related proteins. SSXT (also known as SS18) appears to function synergistically with RBM14 as a transcriptional coactivator [ ].The SSXT protein is involved in synovial sarcoma in humans. A SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18) (p11;q11) is characteristic of synovial sarcomas. This translocation fuses the SSXT (SYT) gene from chromosome 18 to either of two homologous genes at Xp11, SSX1 or SSX2 [ ].The SS18 family also includes SS18-like proteins 1 and 2, and GRF1-interacting factors from plants [ ]. SS18-like protein 1 is a transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons [, ].
Short Name  SS18_N
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0 Child Features

3 Gene Families

Trail: ProteinDomain

473 Genes

Trail: ProteinDomain

0 Ontology Annotations

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14 Publications

Trail: ProteinDomain
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