Protein Domain : Translation Initiation factor eIF- 4e IPR001040

Type  Family
Description  Eukaryotic translation initiation factor 4E (eIF-4E) [ ] is a protein thatbinds to the cap structure of eukaryotic cellular mRNAs. eIF-4E recognises and binds the 7-methylguanosine-containing (m7Gppp) cap during an early step in the initiationof protein synthesis and facilitates ribosome binding to a mRNA by inducing the unwinding of its secondary structures. A tryptophan in the central part of the sequence of humaneIF-4E seems to be implicated in cap-binding [ ].
Short Name  TIF_eIF_4E
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0 Child Features

3 Gene Families

Trail: ProteinDomain

333 Genes

Trail: ProteinDomain

3 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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