Protein Domain : Translation Initiation factor eIF- 4e-like IPR023398

Type  Homologous_superfamily
Description  Eukaryotic translation initiation factor 4E (eIF-4E) [ ] is a protein thatbinds to the cap structure of eukaryotic cellular mRNAs. eIF-4E recognises and binds the 7-methylguanosine-containing (m7Gppp) cap during an early step in the initiationof protein synthesis and facilitates ribosome binding to a mRNA by inducing the unwinding of its secondary structures. A tryptophan in the central part of the sequence of humaneIF-4E seems to be implicated in cap-binding [ ].This entry includes a group of eIF4E-like protein. These proteins consist of a curved eight-stranded antiparallel β-sheet, decorated with three helices on the convex face and three smaller helices inserted in connecting loops [ ].
Short Name  TIF_eIF4e-like

0 Child Features

3 Gene Families

333 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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