Protein Domain : PITH domain IPR010400

Type  Domain
Description  This entry represents the PITH domain (derived from Proteasome-Interacting THioredoxin). The protein Txnl1, which is a probable component of the 32kDa 26S proteasome, uses its C-terminal PITH domain to associate specifically with the 26S proteasome [ ].The PITH domain is dominated by a jelly roll β-sandwich structure. The β-sandwich is formed by face-to-face packing of two anti-parallel β-sheets. Another two-stranded β-sheet seals off one end of the β-barrel [ , ].
Short Name  PITH_dom
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0 Child Features

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124 Genes

Trail: ProteinDomain

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12 Publications

Trail: ProteinDomain
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