v5.1.0.3
Glycine data from LIS
Type | Homologous_superfamily |
Description | This superfamily represents a domain found in lipoxygenases.Lipoxygenases ([intenz:1.13.11.-]) are a class of iron-containing dioxygenases which catalyses the hydroperoxidation of lipids, containing a cis,cis-1,4-pentadiene structure. They are common in plants where they may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Plants express a variety of cytosolic isozymes as well as what seems to be a chloroplast isozyme [].The iron atom in lipoxygenases is bound by four ligands, three of which are histidine residues []. Six histidines are conserved in all lipoxygenase sequences, five of them are found clustered in a stretch of 40 amino acids. This region contains two of the three iron-ligands; the other histidines have been shown [] to be important for the activity of lipoxygenases. |
Short Name | Lipoxygenase_dom_3 |