Protein Domain : PGP phosphatase, mitochondrial/chloroplastic IPR027706

Type  Family
Description  Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) ( ) dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol in cardiolipin biosynthesis. Cardiolipin is a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes. The inverted phosphatase motif includes the highly conserved DKD triad [ , ]. In Saccharomyces cerevisiae, Gep4 is required for the stability of respiratory chain supercomplexes and for growth at elevated temperature, in presence of ethidium bromide or in absence of prohibitins []. Chloroplastic phosphatidylglycerophosphate phosphatase is involved in the biosynthesis of phosphatidylglycerol (PG), a phosphoglycerolipid present in chloroplastic thylakoid membranes and has a photosynthetic function [ ].
Short Name  PGP_Pase

0 Child Features

0 Gene Families

97 Genes

1 Ontology Annotations

1 Parent Features

13 Publications

USDA
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