Protein Domain : Elongator complex protein 1 IPR006849

Type  Family
Description  Elongator complex protein 1 (also known as Iki3) is a component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme. The eukaryotic elongator complex has been associated with many cellular activities, including transcriptional elongation [ , ], but its main function is tRNA modification [, ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [].
Short Name  Elp1

0 Child Features

1 Gene Families

67 Genes

2 Ontology Annotations

0 Parent Features

13 Publications

USDA
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