Protein Domain : Small nuclear ribonucleoprotein Prp3, C-terminal domain IPR010541

Type  Domain
Description  This domain is found at the C-terminal end of U4/U6 and U4/U5/U6-small nuclear ribonucleoprotein Prp3, part of the tri-RNA complex that form the spliceosome. Prp3 plays a key role in the recognition of the snRNA duplex. This binding domain, highly conserved amongeukaryotes, interacts with the 3' end of U6 snRNA. It adopts a ferredoxin-like fold, showing a five-stranded mixed β-sheet withthree α-helices, two of them running parallel to the β-strands on one side of the sheet and one on the other. This fold is extendedwith a long β-hairpin, an extra β-strand, an helix and a final loop at the C terminus [, , , ].
Short Name  Prp3_C

0 Child Features

1 Gene Families

168 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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