Protein Domain : E2F-associated phosphoprotein IPR019370

Type  Family
Description  This entry represents E2F binding proteins. E2F transcription factors play an essential role in cell proliferation and apoptosis and their activity is frequently deregulated in human cancers. E2F activity is regulated by a variety of mechanisms, frequently mediated by proteins binding to individual members or a subgroup of the family. E2F-associated phosphoprotein (EAPP)interacts with a subset of E2F factors and influences E2F-dependent promoter activity. EAPP is present throughout the cell cycle but disappears during mitosis [ ].
Short Name  E2F-assoc_phosphoprotein
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0 Child Features

1 Gene Families

Trail: ProteinDomain

60 Genes

Trail: ProteinDomain

0 Ontology Annotations

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13 Publications

Trail: ProteinDomain
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