v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This family represents the C-terminal NAD-binding region of the fatty acyl-coenzyme A reductases (FARs) from plants and animals. FARs catalyse the reduction of fatty acyl-CoA to fatty alcohols [ , ]. Proteins containing this domain also include non-ribosomal peptide synthetases and non-reducing polyketide synthases from Aspergillaceae. Non-ribosomal peptide synthetases are part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins [ ]. Non-reducing polyketide synthases are involved in the secondary metabolite biosynthesis [].Proteins containing this domain also include L-2-aminoadipate reductase from yeast [ ] and carboxylic acid reductase (Car) from bacteria []. |
Short Name | Far_NAD-bd |