Protein Domain : Fatty acyl-coenzyme A reductase, NAD-binding domain IPR013120

Type  Domain
Description  This family represents the C-terminal NAD-binding region of the fatty acyl-coenzyme A reductases (FARs) from plants and animals. FARs catalyse the reduction of fatty acyl-CoA to fatty alcohols [ , ]. Proteins containing this domain also include non-ribosomal peptide synthetases and non-reducing polyketide synthases from Aspergillaceae. Non-ribosomal peptide synthetases are part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins [ ]. Non-reducing polyketide synthases are involved in the secondary metabolite biosynthesis [].Proteins containing this domain also include L-2-aminoadipate reductase from yeast [ ] and carboxylic acid reductase (Car) from bacteria [].
Short Name  Far_NAD-bd

1 Child Features

0 Gene Families

668 Genes

0 Ontology Annotations

0 Parent Features

13 Publications

USDA
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